αconotoxin auib

Selective antagonist of α3β4 nicotinic acetylcholine receptors. Displays > 100-fold selectivity over other receptor subunit combinations including α2β2, α2β4, α3β2, α4β2, α4β4 and α1β1γδ.

α-Conotoxin AuIB TFA，一种选择性α3β4烟碱乙酰胆碱受体(nAChR)的有效拮抗剂，能阻断在非洲爪蟾卵母细胞中表达的α3β4 nAChRs，其IC50值为0.75 μM。