(s)(+)niguldipine hydrochloride

(S)-(+)-Niguldipine hydrochloride 是一种选择性 α1A-AR 拮抗剂，可用于研究抑郁症和癫痫。

Niguldipine Free Base是一种钙通道阻滞剂和拮抗剂，对Cav 3.2的IC50=0.9 μM，可用于研究心血管系统。

Niguldipine is a calcium channel antagonist. Niguldipine shows high affinity to Ca2+ channels and to a subtype of alpha 1-adrenoceptors.

(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist.

R-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker; potassium agonist that activates Ca2+-activated maxi K-channel; alpha1A-adrenoceptor antagonist; antihypertensive agent; Less active enantiomer.