(32-carbonyl)-rmc 5552

(32-Carbonyl)-RMC-5552 is a highly effective mTOR inhibitor, exhibiting inhibitory effects on both mTORC1 and mTORC2 substrate phosphorylation. Specifically, it significantly suppresses the phosphorylation of p-P70S6K-(T389), p-4E-BP1-(T37 36), and p-AKT1 2 3-(S473) with pIC50 values > 9, >9 and 8~9, respectively.