Name: Poloxamer 124 (L44)
Brand: TargetMol
SKU: TSH-00515
Price: 249 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

25 g

¥ 249

现货

生物活性

产品描述	Poloxamer 124 (L44) is a block copolymer of polyoxyethylene and polyoxypropylene with an average molecular weight of 2200. Poloxamer 124 (L44) exhibits oral toxicity in albino rat studies with an LD50 of 5 g/kg and causes eye irritation. Poloxamer 124 (L44) forms thermoreversible hydrogels and is used in pharmaceutical formulation research and biomaterials studies investigating surfactant-mediated drug solubilization, hydrogel phase transition behavior, and polymer-based delivery systems in biological environments.
体内活性	方法:以 0.17 mg/mL Poloxamer 124 (L44) 按 3 mL/h 速率灌胃处理大鼠，持续 1 h，检测淋巴系统脂质转运及肠腔脂质回收率。结果:Poloxamer 124 (L44) 可显著降低大鼠淋巴系统甘油三酯、胆固醇转运量与磷脂输出量，且未影响机体消化吸收功能，肠腔脂质、胆固醇回收率无明显改变 [3]。提示 Poloxamer 124 (L44) 可干扰脂蛋白组装和 / 或脂蛋白自黏膜细胞的外排过程。
别名	泊洛沙姆 124 (L44)

化学信息

分子量	2200 (Average)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

H2O: 160 mg/mL, Sonication is recommended.

Poloxamer 124 (L44)