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Globotriaosylceramide (non-hydroxy) (porcine RBC) 是一种糖鞘脂,存在于哺乳动物细胞膜中,是法布里病的主要致病分子,其水平可通过补充 α-半乳糖苷酶 A 下调。该化合物通过调控共受体CD19的定位来增强 B 细胞受体信号,可作为疫苗佐剂,引导产生广谱且具交叉保护的抗体应答。此外,Globotriaosylceramide (non-hydroxy) (porcine RBC) 还能通过调节成纤维细胞的异质性促进伤口愈合,并减少瘢痕形成。
Globotriaosylceramide (non-hydroxy) (porcine RBC) 是一种糖鞘脂,存在于哺乳动物细胞膜中,是法布里病的主要致病分子,其水平可通过补充 α-半乳糖苷酶 A 下调。该化合物通过调控共受体CD19的定位来增强 B 细胞受体信号,可作为疫苗佐剂,引导产生广谱且具交叉保护的抗体应答。此外,Globotriaosylceramide (non-hydroxy) (porcine RBC) 还能通过调节成纤维细胞的异质性促进伤口愈合,并减少瘢痕形成。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 10 mg | 待询 | 待询 | |
| 50 mg | 待询 | 待询 |
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| 产品描述 | Globotriaosylceramide (non-hydroxy) (porcine RBC) is a glycosphingolipid found in the cell membranes of mammals. It is a central pathogenic molecule in Fabry disease, with its levels modifiable by supplementing α-galactosidase A. This compound enhances B cell receptor signaling by regulating the localization of the coreceptor CD19 and can serve as a vaccine adjuvant, promoting a broad and cross-protective antibody response. Additionally, Globotriaosylceramide (non-hydroxy) (porcine RBC) aids in wound healing and decreases scar formation by modulating fibroblast heterogeneity. |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 |
对于不同动物的给药剂量换算,您也可以参考 更多