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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ZNT8 Polyclonal Antibody 2

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货号 TMAB-14451

Anti-ZNT8 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ZNT8。Anti-ZNT8 Polyclonal Antibody 2 可用于 WB。

Anti-ZNT8 Polyclonal Antibody 2

Anti-ZNT8 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-14451

Anti-ZNT8 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ZNT8。Anti-ZNT8 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-ZNT8 Polyclonal Antibody 2 is a Rabbit antibody targeting ZNT8. Anti-ZNT8 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein (Probable). Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein (Probable). Note=Associated with insulin and glucagon secretory granules (By similarity).
组织特异性In the endocrine pancreas, expressed in insulin-producing beta cells. Expressed at relatively high levels in subcutaneous fat tissue from lean persons; much lower levels in visceral fat, whether from lean or obese individuals, and in subcutaneous fat tissue from obese individuals. Expressed in peripheral blood mononuclear cells, including T-cells and B-cells, with great variation among individuals ranging from negative to strongly positive.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].
抗原信息
免疫原
KLH conjugated synthetic peptide: human ZNT8
抗原种属
Human
基因名称
SLC30A8
基因ID
169026
蛋白名称
Zinc transporter 8
Uniprot ID
Q8IWU4
功能
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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