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Anti-ZNF195 Polyclonal Antibody

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货号 TMAB-14343

Anti-ZNF195 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZNF195。Anti-ZNF195 Polyclonal Antibody 可用于 WB。

Anti-ZNF195 Polyclonal Antibody

Anti-ZNF195 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-14343

Anti-ZNF195 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZNF195。Anti-ZNF195 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-ZNF195 Polyclonal Antibody is a Rabbit antibody targeting ZNF195. Anti-ZNF195 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nuclear
组织特异性Expressed in adult heart, brain, placenta, skeletal muscle and pancreas, and in fetal lung, kidney and brain. There is little expression in adult lung, liver and kidney.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 195 (ZNF195), also known as ZNFP104, is a 629 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF195 is expressed in adult brain, heart, placenta, pancreas and skeletal muscle and in fetal brain, lung and kidney. ZNF195 contains ten C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation. Three isoforms of ZNF195 exist as a result of alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: Human ZNF195
抗原种属
Human
基因名称
ZNF195
基因ID
蛋白名称
Zinc finger protein 195
Uniprot ID
功能
Zinc finger proteins are an important class of eukaryotic DNA binding proteins. The zinc finger motif contains spatially conserved cysteines and histidines, which bind a zinc ion. The most common zinc finger motif is the C2H2 type, which was first identified in the Drosophila segmentation gene, Kruppel. The human genome has several hundred Kruppel related zinc finger genes. About one third of these human Kruppel type genes also code for a highly conserved region, the Kruppel associated box (KRAB domain), comprising approximately 75 amino acids found at the N terminal end. The zinc finger gene ZNF195 contains an N terminal KRAB domain and 14 tandemly repeated Kruppel type zinc finger motifs at its C terminus. ZNF195 may be involved in transcriptional regulation. It is expressed in adult heart, brain, placenta, skeletal muscle and pancreas, and in foetal lung, kidney and brain. There is little expression in adult lung, liver and kidney.
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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