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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ZGPAT Polyclonal Antibody

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货号 TMAB-14314

Anti-ZGPAT Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ZGPAT。Anti-ZGPAT Polyclonal Antibody 可用于 WB。

Anti-ZGPAT Polyclonal Antibody

Anti-ZGPAT Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14314

Anti-ZGPAT Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ZGPAT。Anti-ZGPAT Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-ZGPAT Polyclonal Antibody is a Rabbit antibody targeting ZGPAT. Anti-ZGPAT Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Widely expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ZGPAT is a 531 amino acid protein that contains a G-patch domain, which is typically found within RNA-binding proteins. Proteins that contain the G-patch domain include some tumor suppressor and DNA-damage repair proteins. ZGPAT also contains one C3H1-type zinc finger, which further supports its probable role as an RNA-binding protein. The gene encoding ZGPAT is inactivated via differential methylation in a oligodendroglioma cell line, suggesting that ZGPAT may have utility as a biomarker. There are two isoforms of ZGPAT that are produced as a result of alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ZGPAT
抗原种属
Human
基因名称
ZGPAT
基因ID
84619
蛋白名称
Zinc finger CCCH-type with G patch domain-containing protein
Uniprot ID
Q8N5A5
功能
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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