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Anti-ZDHHC3 Polyclonal Antibody

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货号 TMAB-14282

Anti-ZDHHC3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZDHHC3。Anti-ZDHHC3 Polyclonal Antibody 可用于 WB。

Anti-ZDHHC3 Polyclonal Antibody

Anti-ZDHHC3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-14282

Anti-ZDHHC3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZDHHC3。Anti-ZDHHC3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-ZDHHC3 Polyclonal Antibody is a Rabbit antibody targeting ZDHHC3. Anti-ZDHHC3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Golgi apparatus membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Golgi-specific DHHC (Asp-His-His-Cys) zinc finger protein (GODZ), also known as, Palmitoyltransferase ZDHHC3 or Zinc finger protein 373, is a 327 amino acid protein member of the DHHC palmitoyltransferase family. Localized to the Golgi apparatus membrane, GODZ contains one DHHC-type zinc finger, which is necessary for its palmitoyltransferase activity. GODZ has been implicated in the palmitoylation and regulated trafficking of diverse substrates that function various inhibitory and excitatory synapses. Specifically, it palmitoylates the gamma subunit 2 of GABA(A) receptors, which leads to normal synaptic GABAergic inhibitory function. GODZ also palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. Two isoforms of GODZ exist as a result of alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GODZ/ZNF373
抗原种属
Human
基因名称
ZDHHC3
基因ID
蛋白名称
Palmitoyltransferase ZDHHC3
Uniprot ID
功能
Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi.
化学信息
分子量Theoretical: 34 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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