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Anti-ZAK Polyclonal Antibody

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货号 TMAB-14235

Anti-ZAK Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZAK。Anti-ZAK Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-ZAK Polyclonal Antibody

Anti-ZAK Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-14235

Anti-ZAK Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ZAK。Anti-ZAK Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-ZAK Polyclonal Antibody is a Rabbit antibody targeting ZAK. Anti-ZAK Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:200-800
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Translocates to the nucleus upon ultraviolet B irradiation.
组织特异性Ubiquitously expressed. Isoform 2 is the predominant form in all tissues examined, except for liver, in which isoform 1 is more highly expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ZAK/HCCS4
抗原种属
Human
基因名称
MAP3K20
基因ID
蛋白名称
Mitogen-activated protein kinase kinase kinase 20
Uniprot ID
功能
Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.
化学信息
分子量Theoretical: 91 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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