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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-XPB Polyclonal Antibody

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货号 TMAB-14214

Anti-XPB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 XPB。Anti-XPB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-XPB Polyclonal Antibody

Anti-XPB Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-14214

Anti-XPB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 XPB。Anti-XPB Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-XPB Polyclonal Antibody is a Rabbit antibody targeting XPB. Anti-XPB Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of 5 subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
抗原信息
免疫原
KLH conjugated synthetic peptide: human XPB/ERCC3
抗原种属
Human
基因名称
ERCC3
基因ID
2071
蛋白名称
General transcription and DNA repair factor IIH helicase subunit XPB
Uniprot ID
P19447
功能
ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage.
化学信息
分子量Theoretical: 89 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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