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Anti-XIAP Monoclonal Antibody (2D738)

Synonyms: XLP2, MIHA, ILP1, IAP-3, hIAP-3, hIAP3, BIRC4, API3
货号 TMAT-1179 一键复制产品信息
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Anti-XIAP Monoclonal Antibody (2D738) 是一种 Mouse 抗体，靶向 XIAP。Anti-XIAP Monoclonal Antibody (2D738) 可用于 FCM。

Anti-XIAP Monoclonal Antibody (2D738)

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货号 TMAT-1179

别名 XLP2, MIHA, ILP1, IAP-3, hIAP-3, hIAP3, BIRC4, API3

Anti-XIAP Monoclonal Antibody (2D738) 是一种 Mouse 抗体，靶向 XIAP。Anti-XIAP Monoclonal Antibody (2D738) 可用于 FCM。

Anti-XIAP Monoclonal Antibody (2D738)
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产品介绍

生物活性
产品描述
Anti-XIAP Monoclonal Antibody (2D738) is a Mouse antibody targeting XIAP. Anti-XIAP Monoclonal Antibody (2D738) can be used in FCM.
别名
XLP2, MIHA, ILP1, IAP-3, hIAP-3, hIAP3, BIRC4, API3
Ig Type
IgG2b
克隆号
2D738
反应种属
Human
应用FCM
推荐剂量
FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human XIAP (AA: 1-268) expressed in E. Coli.
抗原种属
Human
基因名称
XIAP
基因ID
331
蛋白名称
E3 ubiquitin-protein ligase XIAP
Uniprot ID
P98170
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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