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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Wnt11 Polyclonal Antibody 2

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货号 TMAB-14185

Anti-Wnt11 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Wnt11。Anti-Wnt11 Polyclonal Antibody 2 可用于 WB。

Anti-Wnt11 Polyclonal Antibody 2

Anti-Wnt11 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-14185

Anti-Wnt11 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Wnt11。Anti-Wnt11 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Wnt11 Polyclonal Antibody 2 is a Rabbit antibody targeting Wnt11. Anti-Wnt11 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse,Human (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted; extracellular space; extracellular matrix.
组织特异性Expressed in fetal lung, kidney, adult heart, liver, skeletal muscle, and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. The name Wnt denotes the relationship of this family to the Drosophila segment polarity gene ”wingless” and to its vertebrate ortholog, Int-1, a mouse proto-oncogene. Transcription of Wnt family genes appears to be developmentally regulated in a precise temporal and spatial manner. The Wnt genes encode cysteine-rich putative glycoproteins which have features typical of secreted growth factors. Wnt-11 is expressed in the tips of ureteric buds and in the perichondrium, a stem cell-like layer that surrounds the future bones and directs their growth and regeneration. Wnt-11 activity is required for cells to undergo correct convergent extension movements during gastrulation. Human Wnt-11 is also expressed in the lung mesenchyme, the urorectal septum, the urogenital folds, the labioscrotal swellings, and the cortex of the adrenal gland. Unlike other Wnt family members, Wnt-11 is not expressed in the neuroepithelium of the central nervous system. Wnt-11, along with Wnt-8c, is ex-pressed in the posterior region of the chick embryo in the caudal paraxial mesoderm that underlies the prospective caudal neural plate. The gene which encodes Wnt-11 maps to human chromosome 11q13.5.
抗原信息
免疫原
Recombinant Protein: mouse Wnt11 protein
抗原种属
Mouse
基因名称
WNT11
基因ID
22411
蛋白名称
Protein Wnt-11
Uniprot ID
P48615
功能
Wnt11 is a non-canonical Wnt which is expressed in androgen-independent prostate cancer cell lines and prostate tumours. It is involved in development, including cardiac and gut development.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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