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Anti-WBSCR14 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 WBSCR14。Anti-WBSCR14 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-WBSCR14 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 WBSCR14。Anti-WBSCR14 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-WBSCR14 Polyclonal Antibody is a Rabbit antibody targeting WBSCR14. Anti-WBSCR14 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in liver, heart, kidney, cerebellum and intestinal tissues. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain. ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of phospho-serine 196. |
| 免疫原 | KLH conjugated synthetic peptide: human WBSCR14/ChREBP |
| 抗原种属 | Human |
| 基因名称 | MLXIPL |
| 基因ID | |
| 蛋白名称 | Carbohydrate-responsive element-binding protein |
| Uniprot ID | |
| 功能 | Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity). |
| 分子量 | Theoretical: 93 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |