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Anti-WBSCR14 Polyclonal Antibody

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货号 TMAB-14163

Anti-WBSCR14 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 WBSCR14。Anti-WBSCR14 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-WBSCR14 Polyclonal Antibody

Anti-WBSCR14 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14163

Anti-WBSCR14 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 WBSCR14。Anti-WBSCR14 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-WBSCR14 Polyclonal Antibody is a Rabbit antibody targeting WBSCR14. Anti-WBSCR14 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in liver, heart, kidney, cerebellum and intestinal tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain. ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of phospho-serine 196.
抗原信息
免疫原
KLH conjugated synthetic peptide: human WBSCR14/ChREBP
抗原种属
Human
基因名称
MLXIPL
基因ID
蛋白名称
Carbohydrate-responsive element-binding protein
Uniprot ID
功能
Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3' (By similarity).
化学信息
分子量Theoretical: 93 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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