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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-WAS Monoclonal Antibody (3I479)

Synonyms: WASP, THC1, THC, SCNX, IMD2
货号 TMAT-1037 一键复制产品信息
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Anti-WAS Monoclonal Antibody (3I479) 是一种 Mouse 抗体，靶向 WAS。Anti-WAS Monoclonal Antibody (3I479) 可用于 IHC,FCM。

Anti-WAS Monoclonal Antibody (3I479)

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货号 TMAT-1037

别名 WASP, THC1, THC, SCNX, IMD2

Anti-WAS Monoclonal Antibody (3I479) 是一种 Mouse 抗体，靶向 WAS。Anti-WAS Monoclonal Antibody (3I479) 可用于 IHC,FCM。

Anti-WAS Monoclonal Antibody (3I479)
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产品介绍

生物活性
产品描述
Anti-WAS Monoclonal Antibody (3I479) is a Mouse antibody targeting WAS. Anti-WAS Monoclonal Antibody (3I479) can be used in IHC,FCM.
别名
WASP, THC1, THC, SCNX, IMD2
Ig Type
IgG2a
克隆号
3I479
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human WAS (AA: 57-170) expressed in E. Coli.
抗原种属
Human
基因名称
WAS
基因ID
7454
蛋白名称
Actin nucleation-promoting factor WAS
Uniprot ID
P42768
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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