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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-WAC Polyclonal Antibody

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货号 TMAB-14153

Anti-WAC Polyclonal Antibody 是一种 Rabbit 抗体，靶向 WAC。Anti-WAC Polyclonal Antibody 可用于 WB。

Anti-WAC Polyclonal Antibody

Anti-WAC Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14153

Anti-WAC Polyclonal Antibody 是一种 Rabbit 抗体，靶向 WAC。Anti-WAC Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-WAC Polyclonal Antibody is a Rabbit antibody targeting WAC. Anti-WAC Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm > cytoskeleton. Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.
组织特异性Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Spectrin, an Actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous å and ∫ chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin ∫ V is a non-erythrocytic member of the ∫-spectrin family. It is expressed in brain and pancreatic islets and localizes to the cytoplasm of the cytoskeleton and cell cortex. Spectrin ∫ V is a 2,564 amino acid protein with four isoforms due to alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human WAC
抗原种属
Human
基因名称
WAC
基因ID
51332
蛋白名称
WW domain-containing adapter protein with coiled-coil
Uniprot ID
Q9NRC6
功能
Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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