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Anti-VP16 tag Polyclonal Antibody

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货号 TMAB-14126

Anti-VP16 tag Polyclonal Antibody 是一种 Rabbit 抗体，靶向 VP16 tag。Anti-VP16 tag Polyclonal Antibody 可用于 WB,ELISA。

Anti-VP16 tag Polyclonal Antibody

Anti-VP16 tag Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-14126

Anti-VP16 tag Polyclonal Antibody 是一种 Rabbit 抗体，靶向 VP16 tag。Anti-VP16 tag Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-VP16 tag Polyclonal Antibody is a Rabbit antibody targeting VP16 tag. Anti-VP16 tag Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
反应种属
Species independent
应用WBELISA
推荐剂量
WB: 1:1000-5000; ELISA: 1:1000-5000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景HSV evades the immune system through interference with MHC class I antigen presentation on the cell surface, by blocking TAP or the transporter associated with antigen processing induced by the secretion of ICP-47 by HSV. In the host cell, TAP transports digested viral antigen epitope peptides from the cytosol to the endoplasmic reticulum, allowing these epitopes to be combined with MHC class I molecules and presented on the surface of the cell. Viral epitope presentation with MHC class I is a requirement for activation of cytotoxic T-lymphocytes (CTLs), the major effectors of the cell-mediated immune response against virally-infected cells. ICP-47 prevents initiation of a CTL-response against HSV, allowing the virus to survive for a protracted period in the host.
抗原信息
免疫原
KLH conjugated synthetic peptide: HSV-1 VP16
蛋白名称
VP16 tag
功能
Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection (By similarity).
May play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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