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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Vitronectin Polyclonal Antibody

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货号 TMAB-14117

Anti-Vitronectin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Vitronectin。Anti-Vitronectin Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Vitronectin Polyclonal Antibody

Anti-Vitronectin Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14117

Anti-Vitronectin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Vitronectin。Anti-Vitronectin Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Vitronectin Polyclonal Antibody is a Rabbit antibody targeting Vitronectin. Anti-Vitronectin Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space.
组织特异性Plasma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Vitronectin (also known as serum spreading factor, S protein of complement or epibolin) is one of the major multifunctional cell adhesive glycoproteins in mammalian plasma and serum. It is a monomeric acidic glycoprotein detected as a mixture of 75 kD and 65 kD polypeptides. Vitronectin binds to heparin, collagen, streptococci and variety of cultured cells. It also acts as an inhibitor of the complement cascade by binding to the C5b9 complex. Vitronectin promotes cell adhesion and spreading by binding through its cell attachment tripeptide Arg-Gly-Asp (RG-D), activity which is mediated by several different integrin receptors. Apart from the significance for identifying the molecule in the above situations, it also plays an important role in events such as embryonal development, deposition of vitronectin in a number of fibrotic disease states, carcinomas and metastases.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Vitronectin
抗原种属
Human
基因名称
VTN
基因ID
7448
蛋白名称
Vitronectin
Uniprot ID
P04004
功能
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity).
化学信息
分子量Theoretical: 9/52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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