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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-VEGFA Monoclonal Antibody (6N770)

Synonyms: VPF, VEGF, MVCD1
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Anti-VEGFA Monoclonal Antibody (6N770) 是一种 Mouse 抗体，靶向 VEGFA。Anti-VEGFA Monoclonal Antibody (6N770) 可用于 WB,IF。

Anti-VEGFA Monoclonal Antibody (6N770)

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Rating icon 还可以
货号 TMAT-0855

别名 VPF, VEGF, MVCD1

Anti-VEGFA Monoclonal Antibody (6N770) 是一种 Mouse 抗体，靶向 VEGFA。Anti-VEGFA Monoclonal Antibody (6N770) 可用于 WB,IF。

Anti-VEGFA Monoclonal Antibody (6N770)
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产品介绍

生物活性
产品描述
Anti-VEGFA Monoclonal Antibody (6N770) is a Mouse antibody targeting VEGFA. Anti-VEGFA Monoclonal Antibody (6N770) can be used in WB,IF.
别名
VPF, VEGF, MVCD1
Ig Type
IgG1
克隆号
6N770
反应种属
Human
应用WBIF
推荐剂量
WB: 1/500-1/2000; IF: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human VEGFA (AA: 207-371) expressed in E. Coli.
抗原种属
Human
基因名称
VEGFA
基因ID
7422
蛋白名称
Vascular endothelial growth factor A, long form
Uniprot ID
P15692
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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