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Anti-VAV1 Monoclonal Antibody (8R399) 是一种 Mouse 抗体,靶向 VAV1。Anti-VAV1 Monoclonal Antibody (8R399) 可用于 WB,FCM。
别名 VAV
Anti-VAV1 Monoclonal Antibody (8R399) 是一种 Mouse 抗体,靶向 VAV1。Anti-VAV1 Monoclonal Antibody (8R399) 可用于 WB,FCM。

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| 产品描述 | Anti-VAV1 Monoclonal Antibody (8R399) is a Mouse antibody targeting VAV1. Anti-VAV1 Monoclonal Antibody (8R399) can be used in WB,FCM. |
| 别名 | VAV |
| Ig Type | IgG1 |
| 克隆号 | 8R399 |
| 反应种属 | Human |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human VAV1 (AA: 121-324) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | VAV1 |
| 基因ID | |
| 蛋白名称 | Proto-oncogene vav |
| Uniprot ID |
| 分子量 | Theoretical: 98.3 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |