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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-UHRF1 Polyclonal Antibody

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货号 TMAB-13984

Anti-UHRF1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 UHRF1。Anti-UHRF1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-UHRF1 Polyclonal Antibody

Anti-UHRF1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13984

Anti-UHRF1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 UHRF1。Anti-UHRF1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-UHRF1 Polyclonal Antibody is a Rabbit antibody targeting UHRF1. Anti-UHRF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in thymus, bone marrow, testis, lung and heart. Overexpressed in breast cancer.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014]
抗原信息
免疫原
KLH conjugated synthetic peptide: human UHRF1
抗原种属
Human
基因名称
UHRF1
基因ID
29128
蛋白名称
E3 ubiquitin-protein ligase UHRF1
功能
Putative E3 ubiquitin-protein ligase. May participate in methylation-dependent transcriptional regulation. Binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. Important for G1/S transition. May be involved in DNA repair and chromosomal stability.
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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