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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-UBR5 Polyclonal Antibody

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货号 TMAB-13961

Anti-UBR5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 UBR5。Anti-UBR5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-UBR5 Polyclonal Antibody

Anti-UBR5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13961

Anti-UBR5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 UBR5。Anti-UBR5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-UBR5 Polyclonal Antibody is a Rabbit antibody targeting UBR5. Anti-UBR5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Widely expressed. Most abundant in testis and expressed at high levels in brain, pituitary and kidney.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景EDD is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.
抗原信息
免疫原
KLH conjugated synthetic peptide: human EDD
抗原种属
Human
基因名称
UBR5
基因ID
51366
蛋白名称
E3 ubiquitin-protein ligase UBR5
Uniprot ID
O95071
功能
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). May be involved in maturation and/or transcriptional regulation of mRNA. May play a role in control of cell cycle progression. May have tumor suppressor function. Regulates DNA topoisomerase II binding protein (TopBP1) in the DNA damage response. Plays an essential role in extraembryonic development.
化学信息
分子量Theoretical: 309 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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