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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-UBE2J2 Polyclonal Antibody

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货号 TMAB-13936

Anti-UBE2J2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 UBE2J2。Anti-UBE2J2 Polyclonal Antibody 可用于 WB。

Anti-UBE2J2 Polyclonal Antibody

Anti-UBE2J2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13936

Anti-UBE2J2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 UBE2J2。Anti-UBE2J2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-UBE2J2 Polyclonal Antibody is a Rabbit antibody targeting UBE2J2. Anti-UBE2J2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Single-pass type IV membrane protein (By similarity).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human UBE2J2
抗原种属
Human
基因名称
UBE2J2
基因ID
118424
蛋白名称
Ubiquitin-conjugating enzyme E2 J2
Uniprot ID
Q8N2K1
功能
Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity).
化学信息
分子量Theoretical: 29 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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