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Anti-Ube2G1 Polyclonal Antibody

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货号 TMAB-13933

Anti-Ube2G1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ube2G1。Anti-Ube2G1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Ube2G1 Polyclonal Antibody

Anti-Ube2G1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13933

Anti-Ube2G1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ube2G1。Anti-Ube2G1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-Ube2G1 Polyclonal Antibody is a Rabbit antibody targeting Ube2G1. Anti-Ube2G1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Mouse,Dog,Pig,Horse,Rabbit,Sheep,Human)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Widely expressed, mainly in skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. In Saccharomyces cerevisiae, ubiquitin-like proteins include Rub1, Ula1, Uba3, Smt3, Ubc2, Ubc12 and Ubc9. Rub1 shares 53% homology with ubiquitin and requires activation via the E2 proteins, including Ula1, Uba3 and Ubc12 in order to conjugate to substrates directed to different proteolytic systems. Ubc4 catalyzes ubiquitination of IkBa in a phosphorylation and SCFB-TRCP dependent manner. In this particular reaction, E1 first transfers ubiquitin to the E2 component Ubc4, and Ubc4 then associates with E3 ligase, which conjugates the poly-ubiquitin chain on a target protein. In this fashion, the chain tags the IkBa for degradation by a proteasome thus lifting the inhibitory effect of IkBa on NFkB and allowing NFkB to enter the nucleus.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Ube2G1/UBC7
抗原种属
Human
基因名称
UBE2G1
基因ID
7326
蛋白名称
Ubiquitin-conjugating enzyme E2 G1
Uniprot ID
P62253
功能
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.
化学信息
分子量Theoretical: 19 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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