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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TRIM41 Polyclonal Antibody

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货号 TMAB-13783

Anti-TRIM41 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TRIM41。Anti-TRIM41 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-TRIM41 Polyclonal Antibody

Anti-TRIM41 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13783

Anti-TRIM41 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TRIM41。Anti-TRIM41 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-TRIM41 Polyclonal Antibody is a Rabbit antibody targeting TRIM41. Anti-TRIM41 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Expressed in multiple tissues with the highest levels in heart and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Tripartite motif-containing protein 41 (TRIM41), also known as RINCK, is a 630 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Localized to both the nucleus and cytoplasm, TRIM41 associates with protein kinase C (PKC) through the C1A domain of PKC. Studies have shown that overexpression of TRIM41 reduces the levels of PKC in cells, whereas knockdown of TRIM41 leads to increased levels of PKC. Thus, it is hypothesized that TRIM41 plays a role in regulating PCK levels in cells, specifically through the ubiquitination of PKC. Four isoforms of TRIM41 exist as a result of alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TRIM41
抗原种属
Human
基因名称
TRIM41
基因ID
90933
蛋白名称
E3 ubiquitin-protein ligase TRIM41
Uniprot ID
Q8WV44
功能
Functions as an E3 ligase that catalyzes the ubiquitin-mediated degradation of protein kinase C.
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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