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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TRIM32 Polyclonal Antibody

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货号 TMAB-13781

Anti-TRIM32 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TRIM32。Anti-TRIM32 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-TRIM32 Polyclonal Antibody

Anti-TRIM32 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13781

Anti-TRIM32 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TRIM32。Anti-TRIM32 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-TRIM32 Polyclonal Antibody is a Rabbit antibody targeting TRIM32. Anti-TRIM32 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Note=Localized in cytoplasmic bodies, usually concentrated around the nucleus
组织特异性Ubiquitous. High expression in brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains; it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse TRIM32
抗原种属
Mouse
基因名称
TRIM32
基因ID
69807
蛋白名称
E3 ubiquitin-protein ligase TRIM32
Uniprot ID
Q8CH72
功能
Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) (By similarity). Ubiquitinates PIAS4/PIASY and promotes its degradation in keratinocytes treated with UVB and TNF-alpha.
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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