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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TRIB3 Polyclonal Antibody 2

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货号 TMAB-13766

Anti-TRIB3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 TRIB3。Anti-TRIB3 Polyclonal Antibody 2 可用于 WB。

Anti-TRIB3 Polyclonal Antibody 2

Anti-TRIB3 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-13766

Anti-TRIB3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 TRIB3。Anti-TRIB3 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-TRIB3 Polyclonal Antibody 2 is a Rabbit antibody targeting TRIB3. Anti-TRIB3 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Highest expression in liver, pancreas, peripheral blood leukocytes and bone marrow. Also highly expressed in a number of primary lung, colon and breast tumors. Expressed in spleen, thymus, and prostate and is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, and kidney.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse TRIB3
抗原种属
Mouse
基因名称
TRIB3
基因ID
57761
蛋白名称
Tribbles homolog 3
功能
Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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