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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-TRAF2 Monoclonal Antibody (2E109)

Synonyms: TRAP3, TRAP, MGC:45012
货号 TMAT-1256 一键复制产品信息
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Anti-TRAF2 Monoclonal Antibody (2E109) 是一种 Mouse 抗体，靶向 TRAF2。Anti-TRAF2 Monoclonal Antibody (2E109) 可用于 IHC,IF,FCM。

Anti-TRAF2 Monoclonal Antibody (2E109)

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Rating icon 还可以
货号 TMAT-1256

别名 TRAP3, TRAP, MGC:45012

Anti-TRAF2 Monoclonal Antibody (2E109) 是一种 Mouse 抗体，靶向 TRAF2。Anti-TRAF2 Monoclonal Antibody (2E109) 可用于 IHC,IF,FCM。

Anti-TRAF2 Monoclonal Antibody (2E109)
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产品介绍

生物活性
产品描述
Anti-TRAF2 Monoclonal Antibody (2E109) is a Mouse antibody targeting TRAF2. Anti-TRAF2 Monoclonal Antibody (2E109) can be used in IHC,IF,FCM.
别名
TRAP3, TRAP, MGC:45012
Ig Type
IgG1
克隆号
2E109
反应种属
Human
应用IHCIFFCM
推荐剂量
IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human TRAF2 (AA: 39-188) expressed in E. Coli.
抗原种属
Human
基因名称
TRAF2
基因ID
7186
蛋白名称
TNF receptor-associated factor 2
Uniprot ID
Q12933
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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