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Anti-TRAF2 Monoclonal Antibody (1X165) 是一种 Mouse 抗体,靶向 TRAF2。Anti-TRAF2 Monoclonal Antibody (1X165) 可用于 WB,FCM。
别名 TRAP3, TRAP, MGC:45012
Anti-TRAF2 Monoclonal Antibody (1X165) 是一种 Mouse 抗体,靶向 TRAF2。Anti-TRAF2 Monoclonal Antibody (1X165) 可用于 WB,FCM。

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| 产品描述 | Anti-TRAF2 Monoclonal Antibody (1X165) is a Mouse antibody targeting TRAF2. Anti-TRAF2 Monoclonal Antibody (1X165) can be used in WB,FCM. |
| 别名 | TRAP3, TRAP, MGC:45012 |
| Ig Type | IgG2b |
| 克隆号 | 1X165 |
| 反应种属 | Human |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human TRAF2 (AA: 39-188) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | TRAF2 |
| 基因ID | |
| 蛋白名称 | TNF receptor-associated factor 2 |
| Uniprot ID |
| 分子量 | Theoretical: 55.8 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |