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Anti-TRAF1 Polyclonal Antibody 2

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货号 TMAB-13715

Anti-TRAF1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 TRAF1。Anti-TRAF1 Polyclonal Antibody 2 可用于 WB。

Anti-TRAF1 Polyclonal Antibody 2

Anti-TRAF1 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-13715

Anti-TRAF1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 TRAF1。Anti-TRAF1 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-TRAF1 Polyclonal Antibody 2 is a Rabbit antibody targeting TRAF1. Anti-TRAF1 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse TRAF1
抗原种属
Mouse
基因名称
TRAF1
基因ID
蛋白名称
TNF receptor-associated factor 1
Uniprot ID
功能
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
化学信息
分子量Theoretical: 46 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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