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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Torsin B Polyclonal Antibody

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货号 TMAB-13685

Anti-Torsin B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Torsin B。Anti-Torsin B Polyclonal Antibody 可用于 WB。

Anti-Torsin B Polyclonal Antibody

Anti-Torsin B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13685

Anti-Torsin B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Torsin B。Anti-Torsin B Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Torsin B Polyclonal Antibody is a Rabbit antibody targeting Torsin B. Anti-Torsin B Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum and nuclear envelope
组织特异性Widely expressed with low levels in brain. Not detected in fetal brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family. Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins. Via its ability to regulate protein folding, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development. TorsinB contains two PKC (protein kinase C) phosphorylations sites, one ATP binding domain and several conserved cysteines and shares 69% amino acid identity with TorsinA, a related family member. Defects in the gene encoding TorsinB are associated with torsion dystonia, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Torsin B
抗原种属
Human
基因名称
TOR1B
基因ID
27348
蛋白名称
Torsin-1B
Uniprot ID
O14657
功能
Torsins are members of the AAA(+) superfamily of ATPases and are present in all multicellular organisms. Torsin B is an ER protein involved implicated in neurogenesis, neuronal migration, axon/dendrite development and synaptogenesis.
化学信息
分子量Theoretical: 36 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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