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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-TOP2A Monoclonal Antibody (2S493)

Synonyms: TP2A, TOP2
货号 TMAT-0811 一键复制产品信息
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Anti-TOP2A Monoclonal Antibody (2S493) 是一种 Mouse 抗体，靶向 TOP2A。Anti-TOP2A Monoclonal Antibody (2S493) 可用于 WB,IHC。

Anti-TOP2A Monoclonal Antibody (2S493)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0811

别名 TP2A, TOP2

Anti-TOP2A Monoclonal Antibody (2S493) 是一种 Mouse 抗体，靶向 TOP2A。Anti-TOP2A Monoclonal Antibody (2S493) 可用于 WB,IHC。

Anti-TOP2A Monoclonal Antibody (2S493)
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产品介绍

生物活性
产品描述
Anti-TOP2A Monoclonal Antibody (2S493) is a Mouse antibody targeting TOP2A. Anti-TOP2A Monoclonal Antibody (2S493) can be used in WB,IHC.
别名
TP2A, TOP2
Ig Type
IgG1
克隆号
2S493
反应种属
Human
应用WBIHC
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human TOP2A (AA: 1100-1530) expressed in E. Coli.
抗原种属
Human
基因名称
TOP2A
基因ID
7153
蛋白名称
DNA topoisomerase 2-alpha
Uniprot ID
P11388
化学信息
分子量Theoretical: 174.4 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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