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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TNIP1 Polyclonal Antibody

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货号 TMAB-13647

Anti-TNIP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TNIP1。Anti-TNIP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-TNIP1 Polyclonal Antibody

Anti-TNIP1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13647

Anti-TNIP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TNIP1。Anti-TNIP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-TNIP1 Polyclonal Antibody is a Rabbit antibody targeting TNIP1. Anti-TNIP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner.
组织特异性Ubiquitous. Strongly expressed in peripheral blood lymphocytes, spleen and skeletal muscle, and is weakly expressed in the brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Abin-1 is a 636 amino acid protein that localizes to both the nucleus and the cytoplasm and is shuttled between the two intercellular regions in a CRM1-dependent manner. Expressed ubiquitously with highest expression in spleen and skeletal muscle, Abin-1 interacts with A20 and, via this interaction, interferes with TRAF2-mediated transactivation signals and effectively inhibits TNF-induced NFⅹB expression. Additionally, Abin-1 can be incorporated into HIV-1 virions and, if overexpressed, can inhibit viral replication. Abin-1 may also play an important role in the regulation of nuclear import and export activities. Multiple isoforms of Abin-1 exist due to alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TNIP1
抗原种属
Human
基因名称
TNIP1
基因ID
10318
蛋白名称
TNFAIP3-interacting protein 1
Uniprot ID
Q15025
功能
Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal (By similarity). Increases cell surface CD4(T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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