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Anti-TMEFF1 Polyclonal Antibody

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货号 TMAB-13583

Anti-TMEFF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TMEFF1。Anti-TMEFF1 Polyclonal Antibody 可用于 WB。

Anti-TMEFF1 Polyclonal Antibody

Anti-TMEFF1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13583

Anti-TMEFF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TMEFF1。Anti-TMEFF1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-TMEFF1 Polyclonal Antibody is a Rabbit antibody targeting TMEFF1. Anti-TMEFF1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted.
组织特异性Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Tomoregulin-1 precursor is a single-pass type I membrane protein thought to be a tumor suppressor in brain cancers. Its expression is down-regulated in these tumors as compared to control brain tissues. In addition, it might also inhibit NODAL and BMP signaling during neural patterning. There are 2 isoforms produced by alternative splicing.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TEFF1
抗原种属
Human
基因名称
TMEFF1
基因ID
蛋白名称
Tomoregulin-1
Uniprot ID
功能
May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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