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Anti-TMEFF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TMEFF1。Anti-TMEFF1 Polyclonal Antibody 可用于 WB。
Anti-TMEFF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TMEFF1。Anti-TMEFF1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-TMEFF1 Polyclonal Antibody is a Rabbit antibody targeting TMEFF1. Anti-TMEFF1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted. |
| 组织特异性 | Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Tomoregulin-1 precursor is a single-pass type I membrane protein thought to be a tumor suppressor in brain cancers. Its expression is down-regulated in these tumors as compared to control brain tissues. In addition, it might also inhibit NODAL and BMP signaling during neural patterning. There are 2 isoforms produced by alternative splicing. |
| 免疫原 | KLH conjugated synthetic peptide: human TEFF1 |
| 抗原种属 | Human |
| 基因名称 | TMEFF1 |
| 基因ID | |
| 蛋白名称 | Tomoregulin-1 |
| Uniprot ID | |
| 功能 | May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers. |
| 分子量 | Theoretical: 37 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |