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Anti-TLR7 Monoclonal Antibody (9A38) 是一种 Mouse 抗体,靶向 TLR7。Anti-TLR7 Monoclonal Antibody (9A38) 可用于 IF,FCM。
别名 TLR7-like, IMD74
Anti-TLR7 Monoclonal Antibody (9A38) 是一种 Mouse 抗体,靶向 TLR7。Anti-TLR7 Monoclonal Antibody (9A38) 可用于 IF,FCM。

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| 产品描述 | Anti-TLR7 Monoclonal Antibody (9A38) is a Mouse antibody targeting TLR7. Anti-TLR7 Monoclonal Antibody (9A38) can be used in IF,FCM. |
| 别名 | TLR7-like, IMD74 |
| Ig Type | IgG2b |
| 克隆号 | 9A38 |
| 反应种属 | Human |
| 应用 | IFFCM |
| 推荐剂量 | IF: 1/50-1/200; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. The human TLR family comprises 11 members. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. For the recognition of structural components in foreign microorganisms, the various TLRs exhibit different patterns of expression as well; in this way for example, TLR-3, -7, and -8 are essential in the recognition of single-stranded RNA viruses. TLR7 senses single-stranded RNA oligonucleotides containing guanosine- and uridine-rich sequences from RNA viruses, a recognition occuring in the endosomes of plasmacytoid dendritic cells and B cells. This gene is predominantly expressed in lung, placenta, and spleen, and is phylogenetically related and lies in close proximity to another family member, TLR8, on chromosome X. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human TLR7 (AA: 420-644) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | TLR7 |
| 基因ID | |
| 蛋白名称 | Toll-like receptor 7 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |