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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TLR4 Antibody (1M331)

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货号 TMAB-13571

Anti-TLR4 Antibody (1M331) 是一种 Mouse 抗体，靶向 TLR4。Anti-TLR4 Antibody (1M331) 可用于 WB。

Anti-TLR4 Antibody (1M331)

Anti-TLR4 Antibody (1M331)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13571

Anti-TLR4 Antibody (1M331) 是一种 Mouse 抗体，靶向 TLR4。Anti-TLR4 Antibody (1M331) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,570
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-TLR4 Antibody (1M331) is a Mouse antibody targeting TLR4. Anti-TLR4 Antibody (1M331) can be used in WB.
Ig Type
IgG1, k
克隆号
1M331
反应种属
Mouse,Human,Rat
应用WB
推荐剂量
WB=1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Highly expressed in placenta, spleen and peripheral blood leukocytes. Detected in monocytes, macrophages, dendritic cells and several types of T-cells.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Toll-like receptor 4 by activating natural immunity, specific immune response involved in the start-up, Toll-like receptor 4 as an important signal transduction transmembrane receptor involved in the toxin-induced inflammation in the pathological process, its mechanisms of control On a growing concern. all regions were either double-stranded or sequenced with an alternatechemistry or covered by high quality data(i.e., phred quality >=30); an attempt was made to resolve all sequencing problems, such as compressions and repeats; all regions were covered by at least one subclone; and the assembly was confirmed by restriction digest, except on the rare occasion of the clone being a YAC. The following abbreviations are used to associate primary accession numbers given in the feature table with their source databases: Em:, EMBL; Sw:, SWISSPROT; Tr:, TREMBL; Wp:, WORMPEP; Information on the WORMPEP database can be found at. TLR-4 plays an important role in microvascular leakage and leukocyte adhesion under the inflammatory condition associated with nonseptic thermal injury.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse TLR4
抗原种属
Mouse
基因名称
TLR4
基因ID
21898
蛋白名称
Toll-like receptor 4
Uniprot ID
Q9QUK6
功能
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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