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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TLK1 Polyclonal Antibody

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货号 TMAB-13569

Anti-TLK1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TLK1。Anti-TLK1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-TLK1 Polyclonal Antibody

Anti-TLK1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13569

Anti-TLK1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TLK1。Anti-TLK1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-TLK1 Polyclonal Antibody is a Rabbit antibody targeting TLK1. Anti-TLK1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Widely expressed. Present in fetal placenta, liver, kidney and pancreas but not heart or skeletal muscle. Also found in adult cell lines. Isoform 3 is ubiquitously expressed in all tissues examined.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human TLK1
抗原种属
Human
基因名称
TLK1
基因ID
9874
蛋白名称
Serine/threonine-protein kinase tousled-like 1
Uniprot ID
Q9UKI8
功能
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.
化学信息
分子量Theoretical: 87 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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