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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-TIP60 Monoclonal Antibody (2V350)

Synonyms: TIP60 (HTATIP)
货号 TMAT-1467 一键复制产品信息
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Anti-TIP60 Monoclonal Antibody (2V350) 是一种 Mouse 抗体，靶向 TIP60。Anti-TIP60 Monoclonal Antibody (2V350) 可用于 IHC。

Anti-TIP60 Monoclonal Antibody (2V350)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1467

别名 TIP60 (HTATIP)

Anti-TIP60 Monoclonal Antibody (2V350) 是一种 Mouse 抗体，靶向 TIP60。Anti-TIP60 Monoclonal Antibody (2V350) 可用于 IHC。

Anti-TIP60 Monoclonal Antibody (2V350)
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产品介绍

生物活性
产品描述
Anti-TIP60 Monoclonal Antibody (2V350) is a Mouse antibody targeting TIP60. Anti-TIP60 Monoclonal Antibody (2V350) can be used in IHC.
别名
TIP60 (HTATIP)
Ig Type
IgG2b
克隆号
2V350
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide.
浓度1 mg/mL
研究背景HTATIP (HIV-1 Tat interacting protein TIP60, about 60kDa) belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A: canonical H2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the most conserved variant across species, functions as both a positive and negative regulator of transcription and is important for chromosome stability. Several homologous protein complexes, such as SWR-C, TIP60 and SRCAP (mammals), have been shown to catalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human TIP60 expressed in E. Coli.
抗原种属
Human
基因名称
KAT5
基因ID
10524
蛋白名称
Histone acetyltransferase KAT5
Uniprot ID
Q92993
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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