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Anti-TIM4 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 TIM4。Anti-TIM4 Polyclonal Antibody 3 可用于 WB。
Anti-TIM4 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 TIM4。Anti-TIM4 Polyclonal Antibody 3 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-TIM4 Polyclonal Antibody 3 is a Rabbit antibody targeting TIM4. Anti-TIM4 Polyclonal Antibody 3 can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein (Potential). |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. Studies have shown that TIM 4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM 1, and that this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM 4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM 4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM 1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma. |
| 免疫原 | KLH conjugated synthetic peptide: mouse TIM4 |
| 抗原种属 | Mouse |
| 基因名称 | TIMD4 |
| 基因ID | |
| 蛋白名称 | T-cell immunoglobulin and mucin domain-containing protein 4 |
| Uniprot ID | |
| 功能 | Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1 (By similarity). |
| 分子量 | Theoretical: 42 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |