购物车
全部删除
您的购物车当前为空
Anti-TIAF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TIAF1。Anti-TIAF1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-TIAF1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TIAF1。Anti-TIAF1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-TIAF1 Polyclonal Antibody is a Rabbit antibody targeting TIAF1. Anti-TIAF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nuclear |
| 组织特异性 | Not detectable in normal kidney and liver. Up-regulated in chronic and acute allograft rejection: expressed in the inflammatory infiltrate and in tubular epithelial cells. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | TIAF-1 (TGF Beta 1-induced antiapoptotic factor 1), also known as MYO18A, MAJN or MYSPDZ, is a TGF Beta 1-induced anti-apoptotic factor that localizes to the nucleus and functions to inhibit the cytotoxic effects of TNF? TRADD and FADD. Two isoforms of mouse TIAF-1 exist and are designated MysPDZ-Alpha and MysPDZ-Beta. MysPDZ-Alpha consists of a KE-rich region, an N-terminal PDZ domain and a prevalent myosin homologous head region, while the MysPDZ-Beta isoform lacks the KE-rich region and PDZ domain. MysPDZ-Alpha is present in most tissues and is known to co-localize with the ER-Golgi complex and with membrane ruffles and filopodia. MysPDZ-Beta is expressed specifically in hematopoietic tissues and cell lines and shows dispersed localization in the cytoplasm. |
| 免疫原 | KLH conjugated synthetic peptide: human TIAF1 |
| 抗原种属 | Human |
| 基因名称 | TIAF1 |
| 基因ID | |
| 蛋白名称 | TGFB1-induced anti-apoptotic factor 1 |
| Uniprot ID | |
| 功能 | This protein inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIP. It is involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation. |
| 分子量 | Theoretical: 12 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |