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Anti-thymidine phosphorylase Polyclonal Antibody

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货号 TMAB-13529

Anti-thymidine phosphorylase Polyclonal Antibody 是一种 Rabbit 抗体,靶向 thymidine phosphorylase。Anti-thymidine phosphorylase Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-thymidine phosphorylase Polyclonal Antibody

Anti-thymidine phosphorylase Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13529

Anti-thymidine phosphorylase Polyclonal Antibody 是一种 Rabbit 抗体,靶向 thymidine phosphorylase。Anti-thymidine phosphorylase Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-thymidine phosphorylase Polyclonal Antibody is a Rabbit antibody targeting thymidine phosphorylase. Anti-thymidine phosphorylase Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Thymidine Phosphorylase
抗原种属
Human
基因名称
TYMP
基因ID
蛋白名称
Thymidine phosphorylase
Uniprot ID
功能
May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro. Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
化学信息
分子量Theoretical: 50 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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