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Anti-TCL3/HOX11 Polyclonal Antibody

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货号 TMAB-13431

Anti-TCL3/HOX11 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TCL3/HOX11。Anti-TCL3/HOX11 Polyclonal Antibody 可用于 WB。

Anti-TCL3/HOX11 Polyclonal Antibody

Anti-TCL3/HOX11 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13431

Anti-TCL3/HOX11 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TCL3/HOX11。Anti-TCL3/HOX11 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-TCL3/HOX11 Polyclonal Antibody is a Rabbit antibody targeting TCL3/HOX11. Anti-TCL3/HOX11 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. The Hox11 gene, termed an orphan homeobox gene, as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. The human Hox11 gene maps to chromosome 10q24 and has been implicated in the chromosomal translocation t(7;10)(q24;q11) that occurs in T-cell acute lymphoblastic leukemia (T-ALL). The t(7:10) translocation occurs between the Hox11 gene and the T-cell receptor (TCR) delta-chain gene and is a result of aberrant physiological recombinational events at the early stages of T-cell development. The Hox11 gene is normally expressed in the splanchnic anlage arising from the splanchnic mesoderm. Homozygous Hox11-deficient mice have no spleen, while all other splanchnic derivatives develop normally. Spleen development starts and proceeds normally in Hox11-deficient mice to a specific stage of embryogenesis, when the spleen anlage becomes fully absorbed.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TCL3/HOX11
抗原种属
Human
基因名称
TLX1
基因ID
3195
蛋白名称
T-cell leukemia homeobox protein 1
Uniprot ID
P31314
功能
Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
化学信息
分子量Theoretical: 34 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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