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Anti-TCHP Polyclonal Antibody

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货号 TMAB-13429

Anti-TCHP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TCHP。Anti-TCHP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-TCHP Polyclonal Antibody

Anti-TCHP Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13429

Anti-TCHP Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TCHP。Anti-TCHP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-TCHP Polyclonal Antibody is a Rabbit antibody targeting TCHP. Anti-TCHP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Cytoplasm. Cell membrane. Mitochondrion.
组织特异性Expressed at high levels in normal urothelial and breast epithelial cells. Also expressed in the smooth muscle and endothelial cells. Reduced expression seen in advanced bladder and breast carcinomas (at protein level). Ubiquitous. Expressed at highest levels in the heart, skeletal muscle, kidney, liver and testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景A tumour suppressor protein which may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TCHP
抗原种属
Human
基因名称
TCHP
基因ID
蛋白名称
Trichoplein keratin filament-binding protein
Uniprot ID
功能
Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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