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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-TBP Monoclonal Antibody (6V266)

Synonyms: TFIID, SCA17, HDL4, GTF2D1, GTF2D
货号 TMAT-0897 一键复制产品信息
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Anti-TBP Monoclonal Antibody (6V266) 是一种 Mouse 抗体，靶向 TBP。Anti-TBP Monoclonal Antibody (6V266) 可用于 WB,IHC,IF,FCM。

Anti-TBP Monoclonal Antibody (6V266)

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Rating icon 还可以
货号 TMAT-0897

别名 TFIID, SCA17, HDL4, GTF2D1, GTF2D

Anti-TBP Monoclonal Antibody (6V266) 是一种 Mouse 抗体，靶向 TBP。Anti-TBP Monoclonal Antibody (6V266) 可用于 WB,IHC,IF,FCM。

Anti-TBP Monoclonal Antibody (6V266)
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产品介绍

生物活性
产品描述
Anti-TBP Monoclonal Antibody (6V266) is a Mouse antibody targeting TBP. Anti-TBP Monoclonal Antibody (6V266) can be used in WB,IHC,IF,FCM.
别名
TFIID, SCA17, HDL4, GTF2D1, GTF2D
Ig Type
IgG1
克隆号
6V266
反应种属
Human
应用WBIHCIFFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 25-42, and expansion of the number of repeats to 45-66 increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human TBP (AA: 1-144) expressed in E. Coli.
抗原种属
Human
基因名称
TBP
基因ID
6908
蛋白名称
TATA-box-binding protein
Uniprot ID
P20226
化学信息
分子量Theoretical: 37.7 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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