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Anti-TBL1X/SMAP55 Polyclonal Antibody

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货号 TMAB-13395

Anti-TBL1X/SMAP55 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TBL1X/SMAP55。Anti-TBL1X/SMAP55 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-TBL1X/SMAP55 Polyclonal Antibody

Anti-TBL1X/SMAP55 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13395

Anti-TBL1X/SMAP55 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TBL1X/SMAP55。Anti-TBL1X/SMAP55 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-TBL1X/SMAP55 Polyclonal Antibody is a Rabbit antibody targeting TBL1X/SMAP55. Anti-TBL1X/SMAP55 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Cow,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus (Probable).
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human TBL1X
抗原种属
Human
基因名称
TBL1X
基因ID
6907
蛋白名称
F-box-like/WD repeat-containing protein TBL1X
Uniprot ID
O60907
功能
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
化学信息
分子量Theoretical: 63 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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