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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TAP2 Polyclonal Antibody

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货号 TMAB-13375

Anti-TAP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TAP2。Anti-TAP2 Polyclonal Antibody 可用于 FCM。

Anti-TAP2 Polyclonal Antibody

Anti-TAP2 Polyclonal Antibody

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货号 TMAB-13375

Anti-TAP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TAP2。Anti-TAP2 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-TAP2 Polyclonal Antibody is a Rabbit antibody targeting TAP2. Anti-TAP2 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TAP2
抗原种属
Human
基因名称
TAP2
基因ID
6891
蛋白名称
Antigen peptide transporter 2
Uniprot ID
Q03519
化学信息
分子量Theoretical: 75 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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