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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SRRM2 Polyclonal Antibody

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货号 TMAB-13163

Anti-SRRM2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SRRM2。Anti-SRRM2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SRRM2 Polyclonal Antibody

Anti-SRRM2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13163

Anti-SRRM2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SRRM2。Anti-SRRM2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-SRRM2 Polyclonal Antibody is a Rabbit antibody targeting SRRM2. Anti-SRRM2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus speckle.
组织特异性Expressed in liver, placenta, and white blood cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The SRm160/300 splicing coactivator, which consists of the serine/arginine (SR)-related nuclear matrix protein and a nuclear matrix antigen, functions in splicing by promoting critical interactions between splicing factors bound to pre-mRNA. This splicing pathway involves five core small nuclear ribonucleoprotein particles (snRNPs) and the SR family proteins, which coordinately bind to pre-mRNA slicing enhancer elements, are required for accurate splice site recognition, and regulate alterative splicing patterns. The recognized splicing enhancer elements, known also as exonic enhancer splicing sequences, are short RNA sequences that are capable of activating weak splice sites in adjacent introns and contain specific binding sites for the serine/arginine (SR)-rich splicing factors. SRm160 and 300 antigens contain domains rich in SR motifs, but are distinctly different from the SR factors as they lack an RNA recognition motif and cannot directly induce RNA splicing. These proteins rather function as coactivators that stabilize the splicing complex and mediate the U1 snRNP-splicing pathway.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SRRM2
抗原种属
Human
基因名称
SRRM2
基因ID
23524
蛋白名称
Serine/arginine repetitive matrix protein 2
Uniprot ID
Q9UQ35
功能
Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNA substrate By similarity. Binds to RNA.
化学信息
分子量Theoretical: 299 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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