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Anti-SPINK5/LEKTI Polyclonal Antibody

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货号 TMAB-13122

Anti-SPINK5/LEKTI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SPINK5/LEKTI。Anti-SPINK5/LEKTI Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SPINK5/LEKTI Polyclonal Antibody

Anti-SPINK5/LEKTI Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13122

Anti-SPINK5/LEKTI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SPINK5/LEKTI。Anti-SPINK5/LEKTI Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-SPINK5/LEKTI Polyclonal Antibody is a Rabbit antibody targeting SPINK5/LEKTI. Anti-SPINK5/LEKTI Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Pig,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Highly expressed in the thymus and stratum corneum. Also found in the oral mucosa, parathyroid gland, Bartholin's glands, tonsils, and vaginal epithelium. Very low levels are detected in lung, kidney, and prostate.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human SPINK5/LEKTI
抗原种属
Human
基因名称
SPINK5
基因ID
11005
蛋白名称
Serine protease inhibitor Kazal-type 5
Uniprot ID
Q9NQ38
功能
Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation-involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin.
化学信息
分子量Theoretical: 118 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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