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Anti-SORL1 Monoclonal Antibody (3M860) 是一种 Mouse 抗体,靶向 SORL1。Anti-SORL1 Monoclonal Antibody (3M860) 可用于 IHC,IF。
别名 SORL1
Anti-SORL1 Monoclonal Antibody (3M860) 是一种 Mouse 抗体,靶向 SORL1。Anti-SORL1 Monoclonal Antibody (3M860) 可用于 IHC,IF。

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| 产品描述 | Anti-SORL1 Monoclonal Antibody (3M860) is a Mouse antibody targeting SORL1. Anti-SORL1 Monoclonal Antibody (3M860) can be used in IHC,IF. |
| 别名 | SORL1 |
| Ig Type | IgG1 |
| 克隆号 | 3M860 |
| 反应种属 | Human |
| 应用 | IHCIF |
| 推荐剂量 | IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human SORL1 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | SORL1 |
| 基因ID | |
| 蛋白名称 | Sortilin-related receptor |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |