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Anti-SORL1 Monoclonal Antibody (3M860)

Synonyms: SORL1
货号 TMAT-1454 一键复制产品信息
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Anti-SORL1 Monoclonal Antibody (3M860) 是一种 Mouse 抗体,靶向 SORL1。Anti-SORL1 Monoclonal Antibody (3M860) 可用于 IHC,IF。

Anti-SORL1 Monoclonal Antibody (3M860)

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Rating icon 还可以
货号 TMAT-1454

别名 SORL1

Anti-SORL1 Monoclonal Antibody (3M860) 是一种 Mouse 抗体,靶向 SORL1。Anti-SORL1 Monoclonal Antibody (3M860) 可用于 IHC,IF。

Anti-SORL1 Monoclonal Antibody (3M860)
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产品介绍


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产品描述
Anti-SORL1 Monoclonal Antibody (3M860) is a Mouse antibody targeting SORL1. Anti-SORL1 Monoclonal Antibody (3M860) can be used in IHC,IF.
别名
SORL1
Ig Type
IgG1
克隆号
3M860
反应种属
Human
应用IHCIF
推荐剂量
IHC: 1/200-1/1000; IF: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide.
浓度1 mg/mL
研究背景SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human SORL1 expressed in E. Coli.
抗原种属
Human
基因名称
SORL1
基因ID
蛋白名称
Sortilin-related receptor
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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