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Anti-SMAD1 Monoclonal Antibody (1E299) 是一种 Mouse 抗体,靶向 SMAD1。Anti-SMAD1 Monoclonal Antibody (1E299) 可用于 WB。
别名 MADR1, MADH1, JV4-1, JV41, BSP-1, BSP1
Anti-SMAD1 Monoclonal Antibody (1E299) 是一种 Mouse 抗体,靶向 SMAD1。Anti-SMAD1 Monoclonal Antibody (1E299) 可用于 WB。

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| 产品描述 | Anti-SMAD1 Monoclonal Antibody (1E299) is a Mouse antibody targeting SMAD1. Anti-SMAD1 Monoclonal Antibody (1E299) can be used in WB. |
| 别名 | MADR1, MADH1, JV4-1, JV41, BSP-1, BSP1 |
| Ig Type | IgG1 |
| 克隆号 | 1E299 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB |
| 推荐剂量 | WB: 1/500-1/2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human SMAD1 (AA: 1-110) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | SMAD1 |
| 基因ID | |
| 蛋白名称 | SMAD family member 1 |
| Uniprot ID |
| 分子量 | Theoretical: 52.3 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |