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Anti-SMAD1 Monoclonal Antibody (1E299)

Synonyms: MADR1, MADH1, JV4-1, JV41, BSP-1, BSP1
货号 TMAT-1346 一键复制产品信息
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Anti-SMAD1 Monoclonal Antibody (1E299) 是一种 Mouse 抗体,靶向 SMAD1。Anti-SMAD1 Monoclonal Antibody (1E299) 可用于 WB。

Anti-SMAD1 Monoclonal Antibody (1E299)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1346

别名 MADR1, MADH1, JV4-1, JV41, BSP-1, BSP1

Anti-SMAD1 Monoclonal Antibody (1E299) 是一种 Mouse 抗体,靶向 SMAD1。Anti-SMAD1 Monoclonal Antibody (1E299) 可用于 WB。

Anti-SMAD1 Monoclonal Antibody (1E299)
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产品介绍


生物活性
产品描述
Anti-SMAD1 Monoclonal Antibody (1E299) is a Mouse antibody targeting SMAD1. Anti-SMAD1 Monoclonal Antibody (1E299) can be used in WB.
别名
MADR1, MADH1, JV4-1, JV41, BSP-1, BSP1
Ig Type
IgG1
克隆号
1E299
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1/500-1/2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human SMAD1 (AA: 1-110) expressed in E. Coli.
抗原种属
Human
基因名称
SMAD1
基因ID
蛋白名称
SMAD family member 1
Uniprot ID
化学信息
分子量Theoretical: 52.3 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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